Personalizing Precision Oncology: From Light Microscope to Molecular Microscope
نویسندگان
چکیده
منابع مشابه
Light Microscope Studies
The location of myelin encephalitogenic or basic protein (BP) in peripheral nervous system (PNS) and central nervous system (CNS) was investigated by immunofluorescence and horseradish peroxidase (HRP) immunocytochemistry. BP or cross-reacting material could be clearly localized to myelin by immunofluorescence and light microscope HRP immunocytochemistry. Fine structural studies proved to be mu...
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We demonstrate a new design for a light-scattering microscope that is convenient to use and that allows simultaneous imaging and light scattering. The design is motivated by the growing use of thermal fluctuations to probe the viscoelastic properties of complex inhomogeneous environments. We demonstrate measurements of an optically nonergodic sample, one of the most challenging light-scattering...
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Brillouin spectroscopy has been used to characterize shear acoustic phonons in materials. However, conventional instruments had slow acquisition times over 10 min per 1 mW of input optical power, and they required two objective lenses to form a 90° scattering geometry necessary for polarization coupling by shear phonons. Here, we demonstrate a confocal Brillouin microscope capable of detecting ...
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advanced technologies in molecular biology and modern experimental biophysics heavily rely not only on the knowledge of structure of essential proteins but also on their structural dynamics. the function of these bimolecular systems and the pathways along which the biological phenomena take place can be determined based on the knowledge of the molecular structure and behavior. as such, the simp...
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Several mycobacteriophages active against mycobacteria have been isolated by Takeya and Yoshimura (1957) using the soil-enrichment technique. Among these phages, B-1 was found to have the broadest host range including virulent strains of tubercle bacilli. In the present investigation the interactions between mycobacteriophage B-1 and its host strain Mycobacterium avium were examined under the l...
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ژورنال
عنوان ژورنال: Journal of the National Comprehensive Cancer Network
سال: 2019
ISSN: 1540-1405,1540-1413
DOI: 10.6004/jnccn.2019.7330